Euchambersia was a "mammal-like reptile" (order Therapsida) of the suborder Therocephalia that lived during the Late Permian epoch, approximately 250 million years ago, in what is now South Africa.

Euchambersia was a unique therocephalian. Euchambersia may have venom glands connected to its canine teeth. Like snakes, the teeth of Euchambersia were adapted to inject venom to kill its prey. A recess behind each canine tooth housed the venom gland, while grooves down the outer sides of the canine teeth delivered the venom into the puncture wound, together with powerful jaws this made it a very efficient predator to hunt the herbivorious dicynodonts and pareiasaurs it encounterd.

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